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AlawamiAZ 50 minutes ago [-]
Not an interventional RCT. This belongs to the useless pile of Vit D observational studies.
Aurornis 1 hours ago [-]
Study was in an elderly cohort with cognitive impairment. This is a cohort more likely to have nutrition and diet problems and spend all of their time indoors. I haven’t found the full study but the results look marginal for a narrow group.
Then there’s this important note in the highlights:
> Higher daily Vitamin D intake may impact cognition in persons with sleep disturbance and MCI.
More is not better with Vitamin D. Correcting deficiencies is good but the mega dosing trend is not.
phoronixrly 1 hours ago [-]
I'd like to add that correcting deficiencies implies seeing a physician to get your dosage right. This is necessary both for Vitamin D and Melatonin.
If you're not a sedentary geriatric with MCI this study is probably not for you.
zulux 1 hours ago [-]
Sadly, many people in northern areas who are otherwise healthy are vitamin D deficient. It can be a side effect of trying to protect from skin cancer.
phoronixrly 1 hours ago [-]
I am not arguing against that. I argue that correcting this deficiency is not in the competence of people who are not medical professionals no matter how many articles they've read on the front page of HN about vit. D.
zulux 1 hours ago [-]
You can very much overdose on Vit D. I suspect your risk tolerance is different than mine.
OutOfHere 1 hours ago [-]
You are speaking nonsense and lies, considering anyone can get themselves tested. Visiting a doctor is not needed for it.
Doctors are in fact notoriously bad when it comes to vitamin D. None of the docs that I have ever visited eagerly tested my level. I always had to beg for a test. Moreover, none of them ever helped me optimize my level. It is tragically dangerous and harmful to rely on them for it.
phoronixrly 49 minutes ago [-]
What conflict of interest would that be? I'm getting paid by big doctor to tell adtech devs with unchecked egos to go ask someone who has actually dedicated 10+ years of their life to study and practice medicine?
OutOfHere 1 hours ago [-]
This guy will get you killed. It is reasonable to maintain a blood level of about 45 ng/mL. This often requires 5000 IU/day, perhaps less in seniors with weaker kidneys, or those with heavy sun exposure which is dangerous for other reasons. You don't need to see a doctor for this, but you do need to get the test done every year or two. Personally I prefer not involving a doctor for any of it.
Nobody disputes that excessive vitamin D is not good, but maintaining a blood level below 45 ng/ml also is not good. Covid studies had ascertained that a level of at least 50 ng/ml was optimal.
Aurornis 56 minutes ago [-]
> This guy will get you killed
Yeah, no. Advising people to correct Vitamin D deficiencies but to avoid overdosing is correct.
I quoted the study. The study agrees that excessive Vitamin D consumption is not good.
WalterGR 1 hours ago [-]
The shortened title is incorrect: the “/“ should be “+”.
bookofjoe 1 hours ago [-]
Fixed
phoronixrly 1 hours ago [-]
Before you start self-medicating -- "participants had a mean age of 67.2±8.9" and this is a study focusing on people with mild cognitive impairment.
You should see a physician before attempting to treat your poor sleep with vitamin D or melatonin.
OutOfHere 1 hours ago [-]
This guy is another murderer. You don't need to see a doctor to take vitamin D or melatonin, although you do need to empirically optimize the dose for what is both optimal and safe.
jimmaswell 1 hours ago [-]
"Self-medicating" with a standard multivitamin is harmless at worst, and so is additional vitamin D supplementation if it's not in the extreme over a long period of time. It has a nonzero chance of helping, and it's a cheap and easy thing to throw into one's routine.
phoronixrly 1 hours ago [-]
Spoken with such confidence! Are you a physician?
OutOfHere 1 hours ago [-]
All those professionals (scientists, doctors, etc.) who for decades told you not to supplement a good dose of vitamin D have been trying to get you killed. Often they work for big pharma or industry interests, and want to peddle million dollar medicines that don't even work right. They would have us live and die in ignorance. It's also no surprise that healthcare expenses are through the roof. Supplemental vitamin D is hurting the business of endocrinologists most of all.
sublinear 28 minutes ago [-]
Why does every health topic on HN attract so much comment spam?
This was posted 2 hours ago, and right now it's the fearmongerers and pedants. I'm expecting the next wave of comments to be the promoters of bad supplement advice and personal blogs. I'm surprised nobody has mentioned peptides or whatever else yet. That's when you know the discussion has really gone to shit.
Nobody wants to honestly discuss vitamin deficiencies and their impact on quality of life? Most people do have deficiencies. Many of them have otherwise unexplained minor symptoms that are proven to be related to mental health. Vitamin D is at the top of the list. It's worth getting checked out in your routine bloodwork during a doctor visit.
The recommended amounts are what is optimal, but what is strictly necessary is usually far lower. That's why people aren't keeling over and why most of them don't care. Most people have suboptimal diets for a million tangential reasons not worth arguing about. Intake may not even be the problem if you have an undiagnosed endocrine or metabolic issue. Lots of people are prediabetic, drink too much, etc.
I don't think this short list of facts will help, but can we get back on track?
Then there’s this important note in the highlights:
> Higher daily Vitamin D intake may impact cognition in persons with sleep disturbance and MCI.
More is not better with Vitamin D. Correcting deficiencies is good but the mega dosing trend is not.
If you're not a sedentary geriatric with MCI this study is probably not for you.
Doctors are in fact notoriously bad when it comes to vitamin D. None of the docs that I have ever visited eagerly tested my level. I always had to beg for a test. Moreover, none of them ever helped me optimize my level. It is tragically dangerous and harmful to rely on them for it.
Nobody disputes that excessive vitamin D is not good, but maintaining a blood level below 45 ng/ml also is not good. Covid studies had ascertained that a level of at least 50 ng/ml was optimal.
Yeah, no. Advising people to correct Vitamin D deficiencies but to avoid overdosing is correct.
I quoted the study. The study agrees that excessive Vitamin D consumption is not good.
You should see a physician before attempting to treat your poor sleep with vitamin D or melatonin.
This was posted 2 hours ago, and right now it's the fearmongerers and pedants. I'm expecting the next wave of comments to be the promoters of bad supplement advice and personal blogs. I'm surprised nobody has mentioned peptides or whatever else yet. That's when you know the discussion has really gone to shit.
Nobody wants to honestly discuss vitamin deficiencies and their impact on quality of life? Most people do have deficiencies. Many of them have otherwise unexplained minor symptoms that are proven to be related to mental health. Vitamin D is at the top of the list. It's worth getting checked out in your routine bloodwork during a doctor visit.
The recommended amounts are what is optimal, but what is strictly necessary is usually far lower. That's why people aren't keeling over and why most of them don't care. Most people have suboptimal diets for a million tangential reasons not worth arguing about. Intake may not even be the problem if you have an undiagnosed endocrine or metabolic issue. Lots of people are prediabetic, drink too much, etc.
I don't think this short list of facts will help, but can we get back on track?